name: | Policosanol |
ATC code: | C10AX08 | route: | oral |
n-compartments | 1 |
Policosanol is a mixture of long-chain primary aliphatic alcohols derived from plant waxes, commonly including octacosanol as the main component. It has been marketed as a lipid-lowering agent for treatment of hypercholesterolemia and cardiovascular risk management, but its efficacy and regulatory approval is controversial and not approved by major agencies such as FDA or EMA.
No published human pharmacokinetic models with quantifiable parameters are available for policosanol. Available data are limited to general statements about absorption and metabolism after oral administration in healthy adults.