name: | Miconazole |
ATC code: | D01AC02 | route: | oral |
n-compartments | 1 |
Miconazole is an imidazole antifungal medication primarily used to treat superficial fungal infections, such as athlete's foot, ringworm, and candidiasis (including oral and vaginal candidiasis). It functions by inhibiting ergosterol synthesis, disrupting fungal cell membrane integrity. Miconazole is approved and widely used in topical, oral, and occasionally intravenous formulations for the treatment of fungal infections in various countries.
Pharmacokinetics in healthy adult volunteers following oral administration.
Simmons, KB, et al., & Merkatz, R (2018). Effects of concurrent vaginal miconazole treatment on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol delivered from a contraceptive vaginal ring: a randomized, crossover drug-drug interaction study. Contraception 97(3) 270–276. DOI:10.1016/j.contraception.2017.10.010 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29097225
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