.Pharmacolibrary.Drugs.ATC.D.D01AE06

Information

name:D_24ChlorphenoxyEthanol
ATC code:D01AE06
route:topical
n-compartments1

2-(4-chlorophenoxy)-ethanol is an antifungal agent historically used in topical treatments for skin mycoses. It is included in the ATC system under code D01AE06 as a dermatological antifungal. Its application has been mostly topical; the agent is not widely used today and has largely been replaced by other drugs. It is not currently approved for systemic use.

Pharmacokinetics

No published pharmacokinetic studies of 2-(4-chlorphenoxy)-ethanol in humans or animals were found. The following parameters are theoretical estimates for an average adult based on general properties of similar small-molecule topical antifungals.

References

  1. Jin, N, et al., & Müller, RH (2019). Azithromycin nanocrystals for dermal prevention of tick bite infections. Die Pharmazie 74(5) 277–285. DOI:10.1691/ph.2019.8169 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31109397

  2. Baynes, RE, et al., & Riviere, JE (2002). Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phase high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 780(1) 45–52. DOI:10.1016/s1570-0232(02)00412-9 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12383479

Revisions


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