.Pharmacolibrary.Drugs.ATC.D.D04AA12 .Pharmacolibrary.Drugs.ATC.D.D04AA12| name: | Tolpropamine |
| ATC code: | D04AA12 | route: | topical |
| n-compartments | 1 |
Tolpropamine is a first-generation antihistamine belonging to the propylamine class. It possesses anticholinergic and mild sedative properties. Historically, tolpropamine has been used as a topical agent for the relief of pruritus (itching). It is not widely approved or in common use today, with limited availability in modern pharmacopeias.
No published human pharmacokinetic data or primary literature is available on tolpropamine as of June 2024. The following pharmacokinetic parameters are estimated for a hypothetical healthy adult using typical values for first-generation antihistamines.