.Pharmacolibrary.Drugs.ATC.D.D05BA03 .Pharmacolibrary.Drugs.ATC.D.D05BA03| name: | Bergapten | |
| ATC code: | D05BA03 | route: | oral |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 30 | L |
| clearance: | 15 | L/h |
| other parameters in model implementation | ||
Bergapten (5-methoxypsoralen) is a furocoumarin compound primarily found in bergamot and other citrus oils. Historically, it has been used as a photosensitizing agent in the treatment of skin disorders such as psoriasis and vitiligo in combination with UVA phototherapy (PUVA therapy). It is not widely approved for systemic use as a drug today due to safety concerns, particularly phototoxicity and carcinogenicity risks.
Estimated pharmacokinetic parameters for healthy adults administered bergapten orally. No specific clinical pharmacokinetic data for bergapten as a drug in humans found in published studies.