.Pharmacolibrary.Drugs.ATC.D.D06BA01 .Pharmacolibrary.Drugs.ATC.D.D06BA01| name: | SilverSulfadiazine | |
| ATC code: | D06BA01 | route: | topical |
| compartments: | 1 | |
| dosage: | 10000 | mg |
| volume of distribution: | 0.14 | L |
| clearance: | 40 | mL/min |
| other parameters in model implementation | ||
Silver sulfadiazine is a topical antimicrobial agent used primarily for the prevention and treatment of wound infections in patients with second- and third-degree burns. The drug acts by releasing silver ions that are bactericidal and by inhibiting bacterial growth. It is generally applied as a cream and is approved and widely used in clinical burn care.
Pharmacokinetic estimates based on available data in adults with burn wounds; limited systemic absorption occurs through damaged skin, with kinetics mostly described for sulfadiazine component as silver is poorly absorbed.