.Pharmacolibrary.Drugs.ATC.D.D06BB03

Information

Aciclovir is an antiviral medication primarily used for the treatment of infections caused by herpes simplex virus and varicella zoster virus, including genital herpes, cold sores, shingles, and chickenpox. It is available under prescription and remains an approved and commonly used antiviral drug globally.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after single oral dose of 400 mg aciclovir.

References

1. O'Brien, JJ, & Campoli-Richards, DM (1989). Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy. Drugs 37(3) 233–309. DOI:10.2165/00003495-198937030-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2653790

2. Patel, R (1997). Valaciclovir: development, clinical utility and potential. Expert opinion on investigational drugs 6(2) 173–189. DOI:10.1517/13543784.6.2.173 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15989601

3. Noble, S, & Faulds, D (1998). Ganciclovir. An update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients. Drugs 56(1) 115–146. DOI:10.2165/00003495-199856010-00012 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9664203

Revisions

• 06/2025 Tomas Kulhanek, generated model from data extracted from PUBMED, DrugBank and LLM(GPT4.1)