name: | Tirbanibulin | |
ATC code: | D06BX03 | route: | topical |
compartments: | 1 | |
dosage: | 25 | mg |
volume of distribution: | 1 | L |
clearance: | 0 | |
other parameters in model implementation |
Tirbanibulin is a topical synthetic inhibitor of tubulin polymerization and Src kinase signaling, used for the treatment of actinic keratosis. It is approved for use in adults as a 1% ointment applied to the affected area of the skin.
Pharmacokinetic parameters estimated for adults receiving topical application of tirbanibulin 1% ointment. No systemic exposure measured in healthy subjects or patients due to extremely low bioavailability.