.Pharmacolibrary.Drugs.ATC.D.D07AB08 .Pharmacolibrary.Drugs.ATC.D.D07AB08| name: | Desonide | |
| ATC code: | D07AB08 | route: | topical |
| compartments: | 1 | |
| dosage: | 5 | mg |
| volume of distribution: | 2 | L |
| clearance: | 0.15 | L/kg/h |
| other parameters in model implementation | ||
Desonide is a low-potency topical corticosteroid used primarily to treat a variety of skin conditions such as atopic dermatitis, eczema, and psoriasis. It exerts anti-inflammatory and antipruritic effects. Desonide is widely approved and used today, especially suitable for sensitive skin or use in pediatric populations due to its low potency.
Estimated pharmacokinetic parameters for desonide applied topically in adults with healthy skin, as no direct clinical PK studies or compartmental models are published.
Sun, Y, et al., & Yang, G (2024). Evaluation of Bioequivalence and Pharmacokinetic Profiles for Topical Desonide Cream Using Chinese Skins. Skin pharmacology and physiology 37(4-6) 70–79. DOI:10.1159/000540782 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39159613