.Pharmacolibrary.Drugs.ATC.D.D07XC01

Information

name:Betamethasone
ATC code:D07XC01
route:intramuscular
n-compartments2

Betamethasone is a synthetic glucocorticoid corticosteroid with potent anti-inflammatory and immunosuppressive properties. It is used in a range of dermatological, rheumatic, and allergic conditions, as well as for fetal lung maturation in preterm labor. It is an approved and widely used medication today.

Pharmacokinetics

Model parameters are representative for healthy adult volunteers after intramuscular injection of betamethasone phosphate and betamethasone acetate combination, based on typical clinical dosage.

References

  1. Schoenmakers, S, et al., & Koch, BCP (2025). Pharmacokinetics of betamethasone in pre-eclampsia: An in vivo and ex vivo study. British journal of clinical pharmacology None –. DOI:10.1002/bcp.70035 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40083164

  2. Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(2) 261–272. DOI:10.1007/s10928-020-09730-z PUBMED:https://pubmed.ncbi.nlm.nih.gov/33389521

  3. Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(3) 411–438. DOI:10.1007/s10928-021-09755-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/33954911

Revisions


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