.Pharmacolibrary.Drugs.ATC.D.D08AJ02 .Pharmacolibrary.Drugs.ATC.D.D08AJ02| name: | Cetrimonium | |
| ATC code: | D08AJ02 | route: | topical |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 0.2 | L |
| clearance: | 0.01 | L/h/kg |
| other parameters in model implementation | ||
Cetrimonium, also known as cetyltrimethylammonium bromide (CTAB), is a quaternary ammonium compound with antiseptic and surfactant properties. It has been used historically as a topical antiseptic and preservative, predominantly in dermatology for skin and wound disinfection. Today, its clinical use is rare, and it is more commonly found in laboratory and cosmetic applications.
No human in vivo pharmacokinetic study is available for cetrimonium (CTAB) in the published literature. Therefore, the following represents an estimated one-compartment model for topical administration in adults, based on physicochemical properties, class similarity and limited non-clinical data.