.Pharmacolibrary.Drugs.ATC.D.D08AJ03 .Pharmacolibrary.Drugs.ATC.D.D08AJ03| name: | Cetylpyridinium |
| ATC code: | D08AJ03 | route: | oral |
| n-compartments | 1 |
Cetylpyridinium is a quaternary ammonium compound used as an antiseptic and disinfectant, notably in oral hygiene products like mouthwashes and lozenges. It has activity against bacteria and some viruses. It is not systemically used and not approved for any systemic indication, being primarily utilized for topical or mucosal antisepsis.
No pharmacokinetic parameters reported in human subjects; no published studies on systemic pharmacokinetics due to topical use and negligible absorption.
Matsuo, K, et al., & Van Meerbeek, B (2019). Rechargeable anti-microbial adhesive formulation containing cetylpyridinium chloride montmorillonite. Acta biomaterialia 100 388–397. DOI:10.1016/j.actbio.2019.09.045 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31568874
Kozak, KM, et al., & White, DJ (2005). Efficacy of a high bioavailable cetylpyridinium chloride mouthrinse over a 24-hour period: a plaque imaging study. American journal of dentistry 18 Spec No 18A–23A. PUBMED:https://pubmed.ncbi.nlm.nih.gov/16178132