.Pharmacolibrary.Drugs.ATC.D.D08AX03 .Pharmacolibrary.Drugs.ATC.D.D08AX03| name: | Propanol | |
| ATC code: | D08AX03 | route: | oral |
| compartments: | 1 | |
| dosage: | 400 | mg |
| volume of distribution: | 0.7 | L |
| clearance: | 50 | mL/min/kg |
| other parameters in model implementation | ||
Propanol (propanolol) is an antiseptic alcohol primarily used for disinfection of skin and surfaces; it is not generally used systemically or as a pharmaceutical agent for internal use. It is not a currently approved therapeutic drug for systemic treatment in humans. Its main application is topical as a disinfectant.
No pharmacokinetic (PK) parameters for systemic administration of propanol have been published in the scientific literature, as it is exclusively used as a topical disinfectant and not intended for systemic therapy. The following parameters are provided as estimates for hypothetical oral administration in a healthy adult, based on general alcohol absorption and elimination data.
Rasmussen, BB, & Brøsen, K (1996). Determination of urinary metabolites of caffeine for the assessment of cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activity in humans. Therapeutic drug monitoring 18(3) 254–262. DOI:10.1097/00007691-199606000-00006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8738764