.Pharmacolibrary.Drugs.ATC.D.D08AX08

Information

name:Ethanol
ATC code:D08AX08
route:oral
n-compartments1

Ethanol, also known as ethyl alcohol, is a volatile, flammable, colorless liquid commonly used as an antiseptic and disinfectant for topical application, and is the principal psychoactive ingredient in alcoholic beverages. It is not currently used as an approved therapeutic drug but is still in use for certain medical applications, such as antidote therapy in methanol or ethylene glycol poisoning, and for its antimicrobial properties in skin disinfectants.

Pharmacokinetics

Pharmacokinetics in healthy adult volunteers; parameters estimated for intravenous and oral route in typical populations, based on published literature.

References

  1. Büsker, S, et al., & Fuhr, U (2023). Population Pharmacokinetics as a Tool to Reevaluate the Complex Disposition of Ethanol in the Fed and Fasted States. Journal of clinical pharmacology 63(6) 681–694. DOI:10.1002/jcph.2205 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36688276

  2. Knych, HK, et al., & McKemie, DS (2024). Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses. Drug testing and analysis None –. DOI:10.1002/dta.3803 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39279026

  3. Imbert, B, et al., & Simon, N (2016). Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation?. Therapeutic drug monitoring 38(2) 253–258. DOI:10.1097/FTD.0000000000000262 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26580099

Revisions


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