.Pharmacolibrary.Drugs.ATC.D.D10AA03

Information

name:Dexamethasone
ATC code:D10AA03
route:oral
n-compartments2

Dexamethasone is a potent synthetic corticosteroid with anti-inflammatory and immunosuppressant properties. It is widely used to treat conditions such as allergies, skin diseases, rheumatoid disorders, shock, cerebral edema, and as part of some cancer therapies. Dexamethasone is approved and commonly used globally.

Pharmacokinetics

Pharmacokinetic parameters for healthy adults after oral administration. Data is derived from clinical pharmacokinetic studies in volunteers.

References

  1. Wen, J, et al., & Gonzalez, D (2024). Pharmacokinetics of Dexamethasone in Children and Adolescents with Obesity. Journal of clinical pharmacology 64(12) 1491–1504. DOI:10.1002/jcph.6108 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39120865

  2. Wang, X, et al., & Kansra, V (2019). Population Pharmacokinetics of Rolapitant in Patients With Chemotherapy-Induced Nausea and Vomiting. Clinical pharmacology in drug development 8(7) 850–860. DOI:10.1002/cpdd.733 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31418538

  3. Nakade, S, et al., & Miyata, Y (2008). Population pharmacokinetics of aprepitant and dexamethasone in the prevention of chemotherapy-induced nausea and vomiting. Cancer chemotherapy and pharmacology 63(1) 75–83. DOI:10.1007/s00280-008-0713-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/18317761

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos