.Pharmacolibrary.Drugs.ATC.D.D10AB02

Information

name:Sulfur
ATC code:D10AB02
route:topical
n-compartments1

Sulfur is a topical dermatological agent with keratolytic and antibacterial properties, mainly used for the treatment of acne, seborrheic dermatitis, and scabies. While sulfur was widely used historically, it is still available today in various over-the-counter topical preparations for skin conditions.

Pharmacokinetics

No published human pharmacokinetic (PK) study on topical sulfur is available. Systemic absorption thought to be minimal due to topical application; parameters below are estimated based on lack of evidence for systemic exposure.

References

  1. O'Keefe, SJ (2008). Nutrition and colonic health: the critical role of the microbiota. Current opinion in gastroenterology 24(1) 51–58. DOI:10.1097/MOG.0b013e3282f323f3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18043233

  2. Riviere, JE, et al., & Monteiro-Riviere, NA (2003). Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): effects of exposure variables and coadministered toxicants. Journal of toxicology and environmental health. Part A 66(2) 133–151. DOI:10.1080/15287390306400 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12653019

  3. Graham, JS, et al., & Schiavetta, AM (2009). Medical management of cutaneous sulfur mustard injuries. Toxicology 263(1) 47–58. DOI:10.1016/j.tox.2008.07.067 PUBMED:https://pubmed.ncbi.nlm.nih.gov/18762227

Revisions


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