name: | Adapalene |
ATC code: | D10AD03 | route: | topical |
n-compartments | 1 |
Adapalene is a third-generation topical retinoid primarily used for the treatment of acne vulgaris. It acts as a modulator of cellular differentiation, keratinization, and inflammatory processes. Adapalene is approved for use in many countries as a prescription and recently as an over-the-counter medication.
Pharmacokinetic parameters reported for topical adapalene in healthy adult volunteers.
Kumar, V, & Banga, AK (2016). Intradermal and follicular delivery of adapalene liposomes. Drug development and industrial pharmacy 42(6) 871–879. DOI:10.3109/03639045.2015.1082580 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27031916