.Pharmacolibrary.Drugs.ATC.D.D10AF01

Information

Clindamycin is a lincosamide antibiotic used to treat a variety of bacterial infections, including skin, soft tissue, respiratory tract, bone, and joint infections. It is approved and widely used today for susceptible Gram-positive infections and some anaerobic pathogens.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers following oral administration.

References

1. Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866

2. Bouazza, N, et al., & Tréluyer, JM (2012). Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis. British journal of clinical pharmacology 74(6) 971–977. DOI:10.1111/j.1365-2125.2012.04292.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/22486719

3. Armengol Álvarez, L, et al., & Rozenski, J (2022). Ways to Improve Insights into Clindamycin Pharmacology and Pharmacokinetics Tailored to Practice. Antibiotics (Basel, Switzerland) 11(5) –. DOI:10.3390/antibiotics11050701 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35625345

Revisions

• 06/2025 Tomas Kulhanek, generated model from data extracted from PUBMED, DrugBank and LLM(GPT4.1)