.Pharmacolibrary.Drugs.ATC.D.D10AF01_1 .Pharmacolibrary.Drugs.ATC.D.D10AF01_1| name: | Clindamycin_1 |
| ATC code: | D10AF01_1 | route: | intravenous |
| n-compartments | 2 |
Clindamycin is a lincosamide antibiotic used to treat a variety of bacterial infections, including skin, soft tissue, respiratory tract, bone, and joint infections. It is approved and widely used today for susceptible Gram-positive infections and some anaerobic pathogens.
Pharmacokinetic parameters reported for healthy adult volunteers following intravenous administration.
Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866
Bouazza, N, et al., & Tréluyer, JM (2012). Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis. British journal of clinical pharmacology 74(6) 971–977. DOI:10.1111/j.1365-2125.2012.04292.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/22486719
Smith, MJ, et al., & Watt, K (2017). Pharmacokinetics of Clindamycin in Obese and Nonobese Children. Antimicrobial agents and chemotherapy 61(4) –. DOI:10.1128/AAC.02014-16 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28137820