.Pharmacolibrary.Drugs.ATC.D.D11AC06 .Pharmacolibrary.Drugs.ATC.D.D11AC06| name: | PovidoneIodine |
| ATC code: | D11AC06 | route: | topical |
| n-compartments | 1 |
Povidone-iodine is an antiseptic and disinfectant used primarily for skin disinfection before and after surgery, for wound cleaning, and to treat minor infections. It is a complex of polyvinylpyrrolidone and elemental iodine, providing a slow release of iodine. Povidone-iodine is widely used topically and is approved for such uses in many countries.
No explicit pharmacokinetic model data for povidone-iodine exists in literature as it is used almost exclusively topically and is minimally absorbed systemically. No population-, age-, or sex-specific PK data reported.
Lin, YS, et al., & Milgrom, P (2018). Pharmacokinetics of Iodine and Fluoride following Application of an Anticaries Varnish in Adults. JDR clinical and translational research 3(3) 238–245. DOI:10.1177/2380084418771930 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30938600
Below, H, et al., & Rudolph, P (2006). Systemic iodine absorption after preoperative antisepsis using povidone-iodine in cataract surgery-- an open controlled study. Dermatology (Basel, Switzerland) 212 Suppl 1 41–46. DOI:10.1159/000089198 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16490974
Tahirović, H, et al., & Gnat, D (2009). Maternal and neonatal urinary iodine excretion and neonatal TSH in relation to use of antiseptic during caesarean section in an iodine sufficient area. Journal of pediatric endocrinology & metabolism : JPEM 22(12) 1145–1149. DOI:10.1515/jpem.2009.22.12.1145 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20333874