.Pharmacolibrary.Drugs.ATC.D.D11AH06 .Pharmacolibrary.Drugs.ATC.D.D11AH06| name: | Crisaborole |
| ATC code: | D11AH06 | route: | topical |
| n-compartments | 1 |
Crisaborole is a topical phosphodiesterase-4 (PDE4) inhibitor used for the treatment of mild to moderate atopic dermatitis (eczema) in adults and children. It is approved and marketed in several countries for this indication.
Pharmacokinetic parameters reported in healthy adult volunteers following topical application; population includes male and female subjects without atopic dermatitis.
Feng, X, et al., & Zheng, H (2023). A validated UHPLC-MS/MS assay for rapid and sensitive determination of crisaborale in human plasma and its clinico-pharmacokinetic application. Journal of pharmaceutical and biomedical analysis 223 115129–None. DOI:10.1016/j.jpba.2022.115129 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36343536