.Pharmacolibrary.Drugs.ATC.D.D11AX18

Information

name:Diclofenac
ATC code:D11AX18
route:oral
n-compartments2

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used for treating pain and inflammation associated with various conditions, such as arthritis, migraines, and other musculoskeletal disorders. It is widely used and approved in many countries for both short-term and long-term management of pain.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after oral administration of immediate-release diclofenac sodium.

References

  1. Moore, RA, et al., & Straube, S (2015). Effects of food on pharmacokinetics of immediate release oral formulations of aspirin, dipyrone, paracetamol and NSAIDs - a systematic review. British journal of clinical pharmacology 80(3) 381–388. DOI:10.1111/bcp.12628 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25784216

  2. Standing, JF, et al., & Wong, IC (2008). Population pharmacokinetics of oral diclofenac for acute pain in children. British journal of clinical pharmacology 66(6) 846–853. DOI:10.1111/j.1365-2125.2008.03289.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/19032726

  3. Lötsch, J, et al., & Kobal, G (2000). Population pharmacokinetics of fast release oral diclofenac in healthy volunteers: relation to pharmacodynamics in an experimental pain model. Pharmaceutical research 17(1) 77–84. DOI:10.1023/a:1007574710140 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10714612

Revisions


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