.Pharmacolibrary.Drugs.ATC.G.G01AG02 .Pharmacolibrary.Drugs.ATC.G.G01AG02| name: | Terconazole |
| ATC code: | G01AG02 | route: | intravaginal |
| n-compartments | 1 |
Terconazole is a triazole antifungal agent primarily used for the treatment of vulvovaginal candidiasis. It is administered as a topical formulation and is FDA-approved for intravaginal use. Its mechanism of action is through inhibition of fungal cytochrome P450 14α-demethylase, impairing ergosterol synthesis and thus fungal cell membrane formation.
Pharmacokinetic parameters estimated for adult female subjects using intravaginal administration; values are approximated based on summary statements available from product labels and secondary literature, as no detailed compartmental PK modeling for terconazole in humans is published.