name: | PovidoneIodine | |
ATC code: | G01AX11 | route: | vaginal |
compartments: | 1 | |
dosage: | 200 | mg |
volume of distribution: | 1 | L |
clearance: | 0 | |
other parameters in model implementation |
Povidone-iodine is a broad-spectrum antiseptic, consisting of the complex of iodine with povidone (polyvinylpyrrolidone), used for topical disinfection of skin, mucous membranes, wounds, and as a vaginal antiseptic. It is not indicated or approved for systemic use, and its primary application remains as a topical anti-infective agent.
No published human pharmacokinetic models exist for povidone-iodine administered as a vaginal antiseptic or for any other systemic route, as povidone-iodine is intended for topical or local use and not for systemic application. Available literature indicates negligible systemic absorption when used topically or intravaginally in healthy adults.