.Pharmacolibrary.Drugs.ATC.G.G03AB03 .Pharmacolibrary.Drugs.ATC.G.G03AB03| name: | LevonorgestrelAndEthinylestradiol |
| ATC code: | G03AB03 | route: | oral |
| n-compartments | 2 |
Levonorgestrel and ethinylestradiol is a combination of two hormonal agents used primarily as an oral contraceptive for the prevention of pregnancy. Levonorgestrel is a synthetic progestogen, while ethinylestradiol is a synthetic estrogen. This combined oral contraceptive is widely approved and still in active use for birth control in women of reproductive age.
Pharmacokinetic parameters described for healthy female volunteers of reproductive age after administration of a standard combined oral contraceptive tablet containing levonorgestrel 0.15 mg and ethinylestradiol 0.03 mg.
Mohamed, MF, et al., & Othman, AA (2019). The JAK1 Inhibitor Upadacitinib Has No Effect on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol: A Study in Healthy Female Subjects. Journal of clinical pharmacology 59(4) 510–516. DOI:10.1002/jcph.1350 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30500075