name: | Norethisterone |
ATC code: | G03AC01 | route: | oral |
n-compartments | 1 |
Norethisterone (norethindrone) is a synthetic progestin hormone used in hormonal contraceptives, menstrual disorders, and hormone replacement therapy. It is approved and widely used for birth control and to treat conditions such as endometriosis and abnormal uterine bleeding.
Pharmacokinetic parameters reported in healthy adult women after a single oral administration.
Shi, YE, et al., & Fotherby, K (1987). Pharmacokinetics of norethisterone in humans. Contraception 35(5) 465–475. DOI:10.1016/0010-7824(87)90083-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/3621943
Vose, CW, et al., & Serlin, MJ (1979). Bioavailability and pharmacokinetics of norethisterone in women after oral doses of ethynodiol diacetate. Contraception 19(2) 119–127. DOI:10.1016/s0010-7824(79)80024-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/428229
Kiriwat, O, & Fotherby, K (1983). Pharmacokinetics of oral contraceptive steroids after morning or evening administration. Contraception 27(2) 153–160. DOI:10.1016/0010-7824(83)90086-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/6851554