.Pharmacolibrary.Drugs.ATC.G.G03BA03_1

Information

name:Testosterone_1
ATC code:G03BA03_1
route:oral
n-compartments1

Testosterone is a naturally occurring steroid hormone that plays a key role in the development of male reproductive tissues and secondary sexual characteristics. It is used clinically for testosterone replacement therapy in males with hypogonadism and in certain other endocrine disorders. Testosterone is an approved drug for therapeutic use in many countries.

Pharmacokinetics

Population pharmacokinetic model for healthy males following single oral administration of testosterone undecanoate.

References

  1. Bhat, SZ, & Dobs, AS (2022). Testosterone Replacement Therapy: A Narrative Review with a Focus on New Oral Formulations. TouchREVIEWS in endocrinology 18(2) 133–140. DOI:10.17925/EE.2022.18.2.133 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36694887

  2. Roth, MY, et al., & Amory, JK (2011). Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride. International journal of andrology 34(6 Pt 1) 541–547. DOI:10.1111/j.1365-2605.2010.01120.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/20969601

  3. Amory, JK, et al., & Bremner, WJ (2003). Oral testosterone-triglyceride conjugate in rabbits: single-dose pharmacokinetics and comparison with oral testosterone undecanoate. Journal of andrology 24(5) 716–720. DOI:10.1002/j.1939-4640.2003.tb02732.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/12954663

Revisions


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