.Pharmacolibrary.Drugs.ATC.G.G03CA07

Information

name:Estrone
ATC code:G03CA07
route:oral
n-compartments1

Estrone is a naturally occurring estrogenic hormone and a member of the estrogen class of hormones. Used primarily in hormone replacement therapy for menopausal symptoms, it is rarely used today as other estrogens such as estradiol are preferred. Estrone may also be found as part of combination hormone preparations.

Pharmacokinetics

Estimated pharmacokinetic parameters for adult women; no direct published source available. Parameter values extrapolated from known estrone pharmacokinetic properties as reported in reviews and pharmacology reference texts.

References

  1. Doll, E, et al., & Sarvaideo, JL (2022). Pharmacokinetics of Sublingual Versus Oral Estradiol in Transgender Women. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 28(3) 237–242. DOI:10.1016/j.eprac.2021.11.081 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34781041

  2. Stehman-Breen, C, et al., & Ott, S (2003). Pharmacokinetics of oral micronized beta-estradiol in postmenopausal women receiving maintenance hemodialysis. Kidney international 64(1) 290–294. DOI:10.1046/j.1523-1755.2003.00073.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/12787421

  3. Zhang, L, et al., & Shentu, J (2024). Pharmacokinetics and Safety of Estradiol Valerate Tablet and Its Generic: A Phase 1 Bioequivalence Study in Healthy Chinese Postmenopausal Female Subjects. Drug design, development and therapy 18 2891–2904. DOI:10.2147/DDDT.S460681 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39006193

Revisions


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