.Pharmacolibrary.Drugs.ATC.G.G03DA02_1

Information

name:Medroxyprogesterone_1
ATC code:G03DA02_1
route:oral
n-compartments1

Medroxyprogesterone is a synthetic progestin, a derivative of progesterone, used primarily for hormone replacement therapy, treatment of endometriosis, dysmenorrhea, and as a component of some contraceptive formulations. It is available in both oral and injectable forms. Medroxyprogesterone acetate (MPA) is the main clinically used form. This drug is approved and in current therapeutic use.

Pharmacokinetics

Pharmacokinetic parameters following a single 10 mg oral dose of medroxyprogesterone acetate in healthy adult women.

References

  1. Garza-Flores, J, et al., & Perez-Palacios, G (1991). Long-acting hormonal contraceptives for women. The Journal of steroid biochemistry and molecular biology 40(4-6) 697–704. DOI:10.1016/0960-0760(91)90293-e PUBMED:https://pubmed.ncbi.nlm.nih.gov/1958567

  2. Sachdeva, R, et al., & Merkatz, RB (2023). New approaches for developing biomarkers of hormonal contraceptive use. Scientific reports 13(1) 245–None. DOI:10.1038/s41598-022-24215-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36604469

  3. Hall, PE (1987). Once-a-month injectable contraceptives. IPPF medical bulletin 21(2) 1–2. PUBMED:https://pubmed.ncbi.nlm.nih.gov/12268597

Revisions


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