.Pharmacolibrary.Drugs.ATC.G.G03DB04

Information

name:Nomegestrol
ATC code:G03DB04
route:oral
compartments:1
dosage:2.5mg
volume of distribution:1.645L
clearance:26L/h
other parameters in model implementation

Nomegestrol is a synthetic progestogen derived from 19-norprogesterone. It is primarily used as a hormonal contraceptive, often in combination with estrogens, and for the treatment of menstrual disorders. Nomegestrol acetate is approved for clinical use in several countries as an oral progestogen, especially in contraceptive pills.

Pharmacokinetics

Pharmacokinetic parameters for healthy, premenopausal women administered nomegestrol acetate orally as a single dose or as multiple daily doses as part of contraceptive studies.

References

  1. Post, TM, et al., & de Greef, R (2016). Prediction of nomegestrol acetate pharmacokinetics in healthy female adolescents and adults by whole-body physiology-based pharmacokinetic modelling and clinical validation. Contraception 93(2) 133–138. DOI:10.1016/j.contraception.2015.08.017 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26365792

Revisions


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