.Pharmacolibrary.Drugs.ATC.G.G03FA02

Information

name:HydroxyprogesteroneAndEstrogen
ATC code:G03FA02
route:intramuscular
n-compartments1

Combination of hydroxyprogesterone and estrogen used historically for menopausal hormone therapy and other gynecological indications. Currently, this combination is rarely used and is not a standard approved therapy in most countries.

Pharmacokinetics

No published pharmacokinetic studies exist for the fixed combination of hydroxyprogesterone and estrogen (G03FA02) in humans. The following estimates are based on generic known parameters of hydroxyprogesterone caproate and estradiol valerate individually, administered intramuscularly in adult females.

References

  1. Zahradnik, HP (1995). [Depot gestagens]. Archives of gynecology and obstetrics 257(1-4) 536–541. DOI:10.1007/BF02264884 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8579439

  2. Zhou, XF, et al., & Sang, GW (1998). Pharmacokinetics of medroxyprogesterone acetate after single and multiple injection of Cyclofem in Chinese women. Contraception 57(6) 405–411. DOI:10.1016/s0010-7824(98)00048-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9693401

Revisions

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