.Pharmacolibrary.Drugs.ATC.G.G03FA04

Information

name:ProgesteroneAndEstrogen
ATC code:G03FA04
route:oral
n-compartments1

The fixed-dose combination of progesterone and estrogen (with ATC code G03FA04) is used in hormone replacement therapy, particularly for menopausal symptoms such as hot flashes and osteoporosis prevention. It is an approved medication in several countries and is mostly administered orally.

Pharmacokinetics

Pharmacokinetic parameters are estimated for a typical healthy adult female population receiving oral administration, as no published studies have specifically reported full model parameters for this fixed combination.

References

  1. Beumer, JH, & Foldi, J (2023). Pharmacology and pharmacokinetics of elacestrant. Cancer chemotherapy and pharmacology 92(2) 157–163. DOI:10.1007/s00280-023-04550-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37314500

  2. Olsson, B, & Landgren, BM (2001). The effect of tolterodine on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive containing ethinyl estradiol and levonorgestrel. Clinical therapeutics 23(11) 1876–1888. DOI:10.1016/s0149-2918(00)89083-9 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11768839

  3. Yonkers, KA, et al., & Blumenthal, S (1992). Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication. The American journal of psychiatry 149(5) 587–595. DOI:10.1176/ajp.149.5.587 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1575248

Revisions


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