.Pharmacolibrary.Drugs.ATC.G.G04BD06

Information

Propiverine is an antimuscarinic drug used for the treatment of overactive bladder and urinary incontinence. It acts by inhibiting acetylcholine on smooth muscle in the urinary bladder. The drug is approved and currently used in clinical practice for management of urinary frequency, urgency, and urge incontinence.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after single oral administration.

References

1. Weiss, M (2023). Is the One-Compartment Model with First Order Absorption a Useful Approximation?. Pharmaceutical research 40(9) 2147–2153. DOI:10.1007/s11095-023-03582-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37594592

2. Weiss, M, & Siegmund, W (2023). Dependence of Bioavailability on Mean Absorption Time: What Does It Tell Us?. The AAPS journal 25(3) 36–None. DOI:10.1208/s12248-023-00803-8 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37016156

3. Guay, DR (2003). Clinical pharmacokinetics of drugs used to treat urge incontinence. Clinical pharmacokinetics 42(14) 1243–1285. DOI:10.2165/00003088-200342140-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14606931

Revisions

• 06/2025 initial generated model