.Pharmacolibrary.Drugs.ATC.G.G04BE07_1 .Pharmacolibrary.Drugs.ATC.G.G04BE07_1| name: | Apomorphine_1 |
| ATC code: | G04BE07_1 | route: | subcutaneous |
| n-compartments | 2 |
Apomorphine is a non-ergoline dopamine agonist used primarily in the treatment of motor fluctuations ('off' episodes) in Parkinson's disease. It is administered as a rescue medication for rapid symptom relief. It is approved for subcutaneous use and is not typically administered orally due to extensive first-pass metabolism and very low oral bioavailability.
Pharmacokinetic parameters in patients with Parkinson's disease (mean 65 years), multiple subcutaneous doses (5-10 mg).
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