.Pharmacolibrary.Drugs.ATC.G.G04BX15

Information

name:PentosanPolysulfateSodium
ATC code:G04BX15
route:oral
n-compartments1

Pentosan polysulfate sodium (PPS) is a semi-synthetic sulfated polysaccharide chemically related to heparin. It is primarily used in the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS) and is approved for oral use in this indication in several countries. PPS may also have anticoagulant and anti-inflammatory properties. Its precise mechanism in IC is unclear but may involve glycosaminoglycan layer repair within the bladder.

Pharmacokinetics

Oral pharmacokinetic data reported in healthy adult volunteers. Data is limited and absorption is generally poor. Renal excretion is minimal.

References

    Revisions

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