.Pharmacolibrary.Drugs.ATC.G.G04BX16 .Pharmacolibrary.Drugs.ATC.G.G04BX16| name: | Tiopronin |
| ATC code: | G04BX16 | route: | oral |
| n-compartments | 1 |
Tiopronin is a thiol-containing compound used primarily for the prevention of cystine stone formation in patients with severe homozygous cystinuria. It acts by forming a mixed disulfide with cystine, making it more soluble and thus preventing stone formation. Tiopronin is an FDA-approved medication and remains available for clinical use.
Pharmacokinetic parameters estimated for a typical adult population (18-65 years, both sexes, without significant renal or hepatic impairment). Specific PK studies in humans are limited.