name: | TamsulosinAndTadalafil |
ATC code: | G04CA54 | route: | oral |
n-compartments | 2 |
Tamsulosin and tadalafil is a fixed-dose combination used primarily in the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in adult men, with tamsulosin acting as an alpha-1 adrenergic antagonist and tadalafil as a phosphodiesterase-5 inhibitor. The combination is approved and used today for such indications in some countries.
No published pharmacokinetic models providing compartmental parameters for the tamsulosin and tadalafil fixed-dose combination exist as of June 2024. Therefore, estimated parameters are based on known pharmacokinetics of individual oral tamsulosin and tadalafil in healthy adult males.