.Pharmacolibrary.Drugs.ATC.H.H01BA02_2 .Pharmacolibrary.Drugs.ATC.H.H01BA02_2| name: | Desmopressin_2 |
| ATC code: | H01BA02_2 | route: | oral |
| n-compartments | 1 |
Desmopressin is a synthetic analogue of the natural pituitary hormone vasopressin. It is primarily used in the treatment of diabetes insipidus, nocturnal enuresis, and certain bleeding disorders such as hemophilia A and von Willebrand's disease. The drug is approved and widely used today.
Pharmacokinetic parameters after oral administration in healthy adults.
Li, X, et al., & Ding, Y (2018). Pharmacokinetics and safety profile of desmopressin oral tablet formulations in healthy Chinese subjects under fasting and fed conditions. International journal of clinical pharmacology and therapeutics 56(9) 434–442. DOI:10.5414/CP203241 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30049304
Gasthuys, E, et al., & Devreese, M (2018). Population Pharmacokinetic Modeling of a Desmopressin Oral Lyophilisate in Growing Piglets as a Model for the Pediatric Population. Frontiers in pharmacology 9 41–None. DOI:10.3389/fphar.2018.00041 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29445339
Gasthuys, E, et al., & Walle, JV (2020). Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review. Paediatric drugs 22(4) 369–383. DOI:10.1007/s40272-020-00401-7 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32507959