.Pharmacolibrary.Drugs.ATC.H.H01BA03 .Pharmacolibrary.Drugs.ATC.H.H01BA03| name: | Lypressin | |
| ATC code: | H01BA03 | route: | intranasal |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 0.2 | L |
| clearance: | 10 | mL/min/kg |
| other parameters in model implementation | ||
Lypressin (lysine vasopressin) is a synthetic analogue of the natural antidiuretic hormone vasopressin, previously used to treat diabetes insipidus, particularly central diabetes insipidus. It acts as a replacement for ADH deficiency by promoting water reabsorption in the renal collecting ducts. Lypressin is no longer widely used, having been replaced by desmopressin for this indication.
No peer-reviewed clinical pharmacokinetic studies specifically reporting parameters for lypressin in humans could be identified. The following are estimated pharmacokinetic values based on general vasopressin analogues and known properties.