.Pharmacolibrary.Drugs.ATC.H.H02AB03 .Pharmacolibrary.Drugs.ATC.H.H02AB03| name: | Fluocortolone | |
| ATC code: | H02AB03 | route: | rectal |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 50 | L |
| clearance: | 10 | L/h |
| other parameters in model implementation | ||
Fluocortolone is a synthetic glucocorticoid corticosteroid used primarily for its anti-inflammatory and immunosuppressive properties. It is mainly applied in the treatment of hemorrhoids and other rectal inflammatory conditions, often as a suppository or ointment. Fluocortolone is not used as a first-line systemic corticosteroid and its current use is largely topical or rectal in some European countries.
Estimated pharmacokinetic parameters for adult humans following rectal administration. No peer-reviewed publications directly reporting detailed pharmacokinetic compartmental parameters were found.