.Pharmacolibrary.Drugs.ATC.H.H03BA02

Information

name:Propylthiouracil
ATC code:H03BA02
route:oral
compartments:1
dosage:100mg
volume of distribution:0.5L
clearance:0.08L/kg/h
other parameters in model implementation

Propylthiouracil is an antithyroid drug used in the management of hyperthyroidism, particularly in Graves' disease and in thyroid storm. It works by inhibiting the synthesis of thyroid hormones. It is generally used when methimazole is not suitable and is still approved for use, though less commonly than in the past due to rare but serious liver toxicity.

Pharmacokinetics

Adults with hyperthyroidism; PK parameters reported after single oral dose in healthy volunteers.

References

    Revisions


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