.Pharmacolibrary.Drugs.ATC.H.H05BX02 .Pharmacolibrary.Drugs.ATC.H.H05BX02| name: | Paricalcitol | |
| ATC code: | H05BX02 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 5 | mg |
| volume of distribution: | 16 | L |
| clearance: | 0.14 | liter/h/kg |
| other parameters in model implementation | ||
Paricalcitol is a synthetic vitamin D analog used mainly to prevent and treat secondary hyperparathyroidism associated with chronic kidney disease (CKD). It is approved for clinical use and available in both intravenous and oral formulations.
Reported pharmacokinetics in adult CKD patients, hemodialysis and peritoneal dialysis patients, following intravenous administration.
Bailie, GR, & Johnson, CA (2002). Comparative review of the pharmacokinetics of vitamin D analogues. Seminars in dialysis 15(5) 352–357. DOI:10.1046/j.1525-139x.2002.00086.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/12358640