.Pharmacolibrary.Drugs.ATC.J.J01AA14 .Pharmacolibrary.Drugs.ATC.J.J01AA14| name: | Sarecycline |
| ATC code: | J01AA14 | route: | oral |
| n-compartments | 1 |
Sarecycline is a narrow-spectrum tetracycline-class antibiotic used primarily for the treatment of moderate to severe acne vulgaris in patients aged 9 years and older. It is approved by the FDA and is characterized by reduced activity against Gram-negative bacteria, aimed at minimizing gastrointestinal side effects and resistance.
Values reported for healthy adult volunteers following oral administration of sarecycline tablet under fasting conditions.
Tao, RE, et al., & Feldman, SR (2023). Oral Tetracycline-Class Drugs in Dermatology: Impact of Food Intake on Absorption and Efficacy. Antibiotics (Basel, Switzerland) 12(7) –. DOI:10.3390/antibiotics12071152 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37508248
Grada, A, et al., & Hanze, E (2022). Sarecycline treatment for acne vulgaris: Rationale for weight-based dosing and limited impact of food intake on clinical efficacy. Dermatologic therapy 35(3) e15275–None. DOI:10.1111/dth.15275 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34923732