name: | Mecillinam |
ATC code: | J01CA11 | route: | oral |
n-compartments | 1 |
Mecillinam is a beta-lactam antibiotic of the penicillin class, specifically an amidinopenicillin, used primarily to treat urinary tract infections caused by Gram-negative bacteria, particularly Escherichia coli. It is approved and is still in clinical use, especially in Scandinavia and some European countries.
Pharmacokinetic parameters in healthy adult volunteers after oral and intravenous administration; typical clinical dosing.
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Birgy, A, et al., & Bonacorsi, S (2021). Clavulanate combinations with mecillinam, cefixime or cefpodoxime against ESBL-producing Enterobacterales frequently associated with blaOXA-1 in a paediatric population with febrile urinary tract infections. The Journal of antimicrobial chemotherapy 76(11) 2839–2846. DOI:10.1093/jac/dkab289 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34453533