name: | AmpicillinCombinations |
ATC code: | J01CA51 | route: | intravenous |
n-compartments | 2 |
Ampicillin in combination with other agents (such as sulbactam or flucloxacillin) is a broad-spectrum beta-lactam antibiotic used primarily for the treatment of a variety of infections including respiratory tract infections, urinary tract infections, meningitis, septicemia, endocarditis, and intra-abdominal infections. These combinations extend the spectrum of ampicillin by inhibiting beta-lactamases. Ampicillin and combinations are approved for medical use today, though they have been partially supplanted by other beta-lactams in resistant infections.
Pharmacokinetics reported for adult healthy subjects after intravenous administration of ampicillin/sulbactam combination.