.Pharmacolibrary.Drugs.ATC.J.J01CA51 .Pharmacolibrary.Drugs.ATC.J.J01CA51| name: | AmpicillinCombinations | |
| ATC code: | J01CA51 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 1000 | mg |
| volume of distribution: | 13 | L |
| clearance: | 14 | L/h |
| other parameters in model implementation | ||
Ampicillin in combination with other agents (such as sulbactam or flucloxacillin) is a broad-spectrum beta-lactam antibiotic used primarily for the treatment of a variety of infections including respiratory tract infections, urinary tract infections, meningitis, septicemia, endocarditis, and intra-abdominal infections. These combinations extend the spectrum of ampicillin by inhibiting beta-lactamases. Ampicillin and combinations are approved for medical use today, though they have been partially supplanted by other beta-lactams in resistant infections.
Pharmacokinetics reported for adult healthy subjects after intravenous administration of ampicillin/sulbactam combination.