.Pharmacolibrary.Drugs.ATC.J.J01DC04

Information

Cefaclor is a second-generation cephalosporin antibiotic used to treat a variety of bacterial infections, including respiratory tract infections, otitis media, skin and soft tissue infections, and urinary tract infections. It is administered primarily orally and is approved for clinical use.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after single oral dose administration.

References

1. Kanan, M, et al., & Hazza, A (2023). A Systematic Review on the Clinical Pharmacokinetics of Cephalexin in Healthy and Diseased Populations. Antibiotics (Basel, Switzerland) 12(9) –. DOI:10.3390/antibiotics12091402 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37760698

2. Chen, J, et al., & Ruan, Z (2012). Bioequivalence studies of 2 oral cefaclor capsule formulations in chinese healthy subjects. Arzneimittel-Forschung 62(3) 134–137. DOI:10.1055/s-0031-1298012 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22286978

3. Langtry, HD, & Balfour, JA (1998). Azithromycin. A review of its use in paediatric infectious diseases. Drugs 56(2) 273–297. DOI:10.2165/00003495-199856020-00014 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9711451

Revisions

• 06/2025 Tomas Kulhanek, generated model from data extracted from PUBMED, DrugBank and LLM(GPT4.1)