.Pharmacolibrary.Drugs.ATC.J.J01FF01

Information

name:Clindamycin
ATC code:J01FF01
route:oral
n-compartments2

Clindamycin is a lincosamide antibiotic used for the treatment of a variety of serious bacterial infections, particularly those caused by susceptible anaerobic bacteria, streptococci, staphylococci, and pneumococci. It is approved and in current clinical use, commonly for skin infections, bone and joint infections, and as an alternative in patients allergic to penicillins.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after a single 300 mg oral dose of clindamycin.

References

  1. Sullins, AK, & Abdel-Rahman, SM (2013). Pharmacokinetics of antibacterial agents in the CSF of children and adolescents. Paediatric drugs 15(2) 93–117. DOI:10.1007/s40272-013-0017-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23529866

  2. Bouazza, N, et al., & Tréluyer, JM (2012). Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis. British journal of clinical pharmacology 74(6) 971–977. DOI:10.1111/j.1365-2125.2012.04292.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/22486719

  3. Armengol Álvarez, L, et al., & Rozenski, J (2022). Ways to Improve Insights into Clindamycin Pharmacology and Pharmacokinetics Tailored to Practice. Antibiotics (Basel, Switzerland) 11(5) –. DOI:10.3390/antibiotics11050701 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35625345

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos