.Pharmacolibrary.Drugs.ATC.J.J01MA12_1

Information

Levofloxacin is a broad-spectrum third-generation fluoroquinolone antibiotic, primarily used for the treatment of bacterial infections such as respiratory tract infections, urinary tract infections, and skin infections. It is approved and widely used in clinical practice today.

Pharmacokinetics

Pharmacokinetic parameters for a single intravenous dose in healthy adult volunteers.

References

1. Setiawan, E, et al., & Roberts, JA (2022). Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients. Scientific reports 12(1) 8930–None. DOI:10.1038/s41598-022-12627-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35624222

2. Zhang, Y, et al., & Sun, L (2014). Population pharmacokinetics of intravenous levofloxacin 500 mg/day dosage in infected patients. Die Pharmazie 69(7) 553–557. PUBMED:https://pubmed.ncbi.nlm.nih.gov/25073403

3. Jaruratanasirikul, S, et al., & Samaeng, M (2018). Population Pharmacokinetics and Pharmacodynamics Modeling of Oral Levofloxacin. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 99(8) 886–892. PUBMED:https://pubmed.ncbi.nlm.nih.gov/29947489

Revisions

• 06/2025 initial generated model