.Pharmacolibrary.Drugs.ATC.J.J01MA21

Information

name:Sitafloxacin
ATC code:J01MA21
route:oral
n-compartments1

Sitafloxacin is a fluoroquinolone antibiotic developed for the treatment of various bacterial infections including respiratory tract infections, urinary tract infections, and others. It exhibits broad-spectrum antibacterial activity. Sitafloxacin is approved and primarily used in Japan and some Asian countries.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult Japanese volunteers after oral administration of sitafloxacin hydrate 100 mg tablet.

References

  1. Paiboonvong, T, et al., & Punyawudho, B (2025). Population Pharmacokinetics and Pharmacodynamics of Sitafloxacin in Plasma and Alveolar Epithelial Lining Fluid of Critically Ill Thai Patients With Pneumonia. Pharmacology research & perspectives 13(2) e70081–None. DOI:10.1002/prp2.70081 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40122675

  2. O'Grady, J, et al., & Milatovic, D (2001). Pharmacokinetics and absolute bioavailability of sitafloxacin, a new fluoroquinolone antibiotic, in healthy male and female Caucasian subjects. Xenobiotica; the fate of foreign compounds in biological systems 31(11) 811–822. DOI:10.1080/0049825011 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11765143

Revisions


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