.Pharmacolibrary.Drugs.ATC.J.J01XA01 .Pharmacolibrary.Drugs.ATC.J.J01XA01| name: | Vancomycin |
| ATC code: | J01XA01 | route: | intravenous |
| n-compartments | 2 |
Vancomycin is a glycopeptide antibiotic used mainly for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant Staphylococcus aureus (MRSA) and other Gram-positive bacteria. It is often reserved for infections that do not respond to other antibiotics and is approved and widely used today especially in hospital settings.
Adult healthy volunteers, intravenous administration, standard dosage.
Goyal, RK, et al., & Al Mohajer, M (2022). Population Pharmacokinetics of Vancomycin in Pregnant Women. Frontiers in pharmacology 13 873439–None. DOI:10.3389/fphar.2022.873439 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35734401
Chen, Z, et al., & Liebchen, U (2023). Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain. Antimicrobial agents and chemotherapy 67(6) e0024123–None. DOI:10.1128/aac.00241-23 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37162349
Yu, Z, et al., & Zhao, Y (2023). Population pharmacokinetics and individualized dosing of vancomycin for critically ill patients receiving continuous renal replacement therapy: the role of residual diuresis. Frontiers in pharmacology 14 1298397–None. DOI:10.3389/fphar.2023.1298397 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38223197